Psychological distress in fibromyalgia patients: A role for catechol-O-methyl-transferase Val158met polymorphism.
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چکیده
منابع مشابه
Catechol-O-methyl transferase and schizophrenia.
Catechol-O-methyl transferase (COMT) is an enzyme involved in the degradation of dopamine. The most commonly examined polymorphism within the COMT gene is Val108/158Met polymorphism, which results in three to fourfold difference in COMT enzyme activity. It is particularely important in prefrontal cortex, since COMT activity is the most important regulator of the prefrontal dopamine function. Gi...
متن کاملCatechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls
Non-psychotic individuals at increased risk for schizophrenia show alterations in fronto-striatal dopamine signaling and cortical gray matter maturation reminiscent of those seen in schizophrenia. It remains unclear however if variations in dopamine signaling influence rates of structural cortical maturation in typically developing individuals, and whether such influences are disrupted in patie...
متن کاملassociation of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia
background : a single nucleotide variation within atechol-o-methyl transferase (comt) gene may alter the comt enzyme activity level. polymorphism of val158met in the comt gene has been related to malignancy. in this regard, a study was carried out to find a possible association between the comt gene polymorphism in patients with sporadic prostate cancer (pca) and benign prostatic hyperplasia (...
متن کاملThe Influence of the Val158Met Catechol-O-Methyltransferase Polymorphism on the Personality Traits of Bipolar Patients
INTRODUCTION Certain personality traits and genetic polymorphisms are contributing factors to bipolar disorder and its symptomatology, and in turn, this syndrome influences personality. The aim of the present study is to compare the personality traits of euthymic bipolar patients with healthy controls and to investigate the effect of the catechol-O-methyltransferase (COMT) Val158Met genotype on...
متن کاملAssociation of catechol-o-methyl transferase gene polymorphism with prostate cancer and benign prostatic hyperplasia
BACKGROUND A single nucleotide variation within catechol-o-methyl transferase (COMT) gene may alter the COMT enzyme activity level. Polymorphism of Val158Met in the COMT gene has been related to malignancy. In this regard, a study was carried out to find a possible association between the COMT gene polymorphism in patients with sporadic prostate cancer (PCa) and benign prostatic hyperplasia (BP...
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ژورنال
عنوان ژورنال: Health Psychology
سال: 2012
ISSN: 1930-7810,0278-6133
DOI: 10.1037/a0025223